Ontology highlight
ABSTRACT:
SUBMITTER: Que Y
PROVIDER: S-EPMC6713642 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Que Yi Y Fang Zhixin Z Guan Yuanxiang Y Xiao Wei W Xu Bushu B Zhao Jingjing J Chen Huoying H Zhang Xinke X Zeng Musheng M Liang Yao Y Zhang Xing X
Cancer biology & medicine 20190501 2
<h4>Objective</h4>To elucidate the role and prognostic significance of lymphocyte activation-gene-3 (LAG-3) in soft tissue sarcoma (STS).<h4>Methods</h4>The expression of LAG-3 in patient and matched normal blood samples was analyzed by flow cytometry. The localization and prognostic values of LAG-3<sup>+</sup> cells in 163 STS patients were analyzed by immunohistochemistry. In addition, the expression of tumor-infiltrating CD3<sup>+</sup> T, CD4<sup>+</sup> T, and CD8<sup>+</sup> T cells and th ...[more]