Ontology highlight
ABSTRACT:
SUBMITTER: Pandi A
PROVIDER: S-EPMC6713752 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Pandi Amir A Koch Mathilde M Voyvodic Peter L PL Soudier Paul P Bonnet Jerome J Kushwaha Manish M Faulon Jean-Loup JL
Nature communications 20190828 1
Synthetic biological circuits are promising tools for developing sophisticated systems for medical, industrial, and environmental applications. So far, circuit implementations commonly rely on gene expression regulation for information processing using digital logic. Here, we present a different approach for biological computation through metabolic circuits designed by computer-aided tools, implemented in both whole-cell and cell-free systems. We first combine metabolic transducers to build an a ...[more]