Ontology highlight
ABSTRACT:
SUBMITTER: Wang W
PROVIDER: S-EPMC6714145 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Wang Weiguo W Li Jinsong J Ding Zhiyu Z Li Yuezhan Y Wang Jianlong J Chen Shijie S Miao Jinglei J
Journal of cellular and molecular medicine 20190710 9
Tanshinone I (Tan I) is a widely used diterpene compound derived from the traditional Chinese herb Danshen. Increasing evidence suggests that it exhibits anti-cancer activity in various human cancers. However, the in vitro and in vivo effects of Tan I on osteosarcoma (OS) remain inadequately elucidated, especially those against tumour metastasis. Our results showed that Tan I significantly inhibited OS cancer cell proliferation, migration and invasion and induced cell apoptosis in vitro. Moreove ...[more]