Dataset Information

Beyond the Low Frequency Fluctuations: Morning and Evening Differences in Human Brain.

ABSTRACT: Human performance, alertness, and most biological functions express rhythmic fluctuations across a 24-h-period. This phenomenon is believed to originate from differences in both circadian and homeostatic sleep-wake regulatory processes. Interactions between these processes result in time-of-day modulations of behavioral performance as well as brain activity patterns. Although the basic mechanism of the 24-h clock is conserved across evolution, there are interindividual differences in the timing of sleep-wake cycles, subjective alertness and functioning throughout the day. The study of circadian typology differences has increased during the last few years, especially research on extreme chronotypes, which provide a unique way to investigate the effects of sleep-wake regulation on cerebral mechanisms. Using functional magnetic resonance imaging (fMRI), we assessed the influence of chronotype and time-of-day on resting-state functional connectivity. Twenty-nine extreme morning- and 34 evening-type participants underwent two fMRI sessions: about 1 h after wake-up time (morning) and about 10 h after wake-up time (evening), scheduled according to their declared habitual sleep-wake pattern on a regular working day. Analysis of obtained neuroimaging data disclosed only an effect of time of day on resting-state functional connectivity; there were different patterns of functional connectivity between morning (MS) and evening (ES) sessions. The results of our study showed no differences between extreme morning-type and evening-type individuals. We demonstrate that circadian and homeostatic influences on the resting-state functional connectivity have a universal character, unaffected by circadian typology.

SUBMITTER: Fafrowicz M

PROVIDER: S-EPMC6718916 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Beyond the Low Frequency Fluctuations: Morning and Evening Differences in Human Brain.

Fafrowicz Magdalena M Bohaterewicz Bartosz B Ceglarek Anna A Cichocka Monika M Lewandowska Koryna K Sikora-Wachowicz Barbara B Oginska Halszka H Beres Anna A Olszewska Justyna J Marek Tadeusz T

Frontiers in human neuroscience 20190827

Human performance, alertness, and most biological functions express rhythmic fluctuations across a 24-h-period. This phenomenon is believed to originate from differences in both circadian and homeostatic sleep-wake regulatory processes. Interactions between these processes result in time-of-day modulations of behavioral performance as well as brain activity patterns. Although the basic mechanism of the 24-h clock is conserved across evolution, there are interindividual differences in the timing ...[more]

PMID: 31507393

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Dataset Information

Beyond the Low Frequency Fluctuations: Morning and Evening Differences in Human Brain.

Publications

Beyond the Low Frequency Fluctuations: Morning and Evening Differences in Human Brain.

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