Ontology highlight
ABSTRACT:
SUBMITTER: Del Re M
PROVIDER: S-EPMC6720634 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Del Re Marzia M Crucitta Stefania S Gianfilippo Giulia G Passaro Antonio A Petrini Iacopo I Restante Giuliana G Michelucci Angela A Fogli Stefano S de Marinis Filippo F Porta Camillo C Chella Antonio A Danesi Romano R
International journal of molecular sciences 20190814 16
Liquid biopsy has emerged as an alternative source of nucleic acids for the management of Epidermal Growth Factor Receptor (<i>EGFR</i>)-mutant non-Small Cell Lung Cancer (NSCLC). The use of circulating cell-free DNA (cfDNA) has been recently introduced in clinical practice, resulting in the improvement of the identification of druggable <i>EGFR</i> mutations for the diagnosis and monitoring of response to targeted therapy. <i>EGFR</i>-dependent (T790M and C797S mutations) and independent (Mesen ...[more]