Ontology highlight
ABSTRACT:
SUBMITTER: Wang TY
PROVIDER: S-EPMC6722118 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Wang Tony Y TY Arking Dan E DE Maleszewski Joseph J JJ Fox-Talbot Karen K Nieuwenhuis Tim O TO Santhanam Lakshmi L Virmani Renu R Rosenberg Avi Z AZ Halushka Marc K MK
Scientific reports 20190903 1
Sex disparities modulate cardiac function, although the proteins and mechanisms remain to be elucidated. We recently demonstrated a mosaic pattern of protein expression in the heart for over 100 proteins. Here we investigate one of these proteins, myosin light chain 4 (MYL4), which is important for contractile functions by increasing force production. We assayed the expression pattern of MYL4 across 756 ventricular myocardial samples from 668 individuals utilizing a semi-automated Cell Profiler ...[more]