Ontology highlight
ABSTRACT:
SUBMITTER: He J
PROVIDER: S-EPMC6723752 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
He Junbo J Huang Shuangshuang S Sun Xiaotao X Han Lijuan L Chang Chao C Zhang Weinong W Zhong Qixin Q
Nanomaterials (Basel, Switzerland) 20190814 8
To develop solid lipid nanoparticles (SLNs) with stable lipid matrix structures for the delivery of bioactive compounds, a new class of SLNs was studied using propylene glycol monopalmitate (PGMP) and glyceryl monostearate (GMS) mixtures and carvacrol as a model lipophilic antimicrobial. Stable SLNs were fabricated at PGMP:GMS mass ratios of 2:1 and 1:1, and the carvacrol loading was up to 30% of lipids with >98% encapsulation efficiency and absence of visual instability. Fluorescence spectra an ...[more]