Ontology highlight
ABSTRACT:
SUBMITTER: Moren B
PROVIDER: S-EPMC6724522 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Morén Björn B Hansson Björn B Negoita Florentina F Fryklund Claes C Lundmark Richard R Göransson Olga O Stenkula Karin G KG
Molecular biology of the cell 20190227 10
Adipocytes play a central role in energy balance, and dysfunctional adipose tissue severely affects systemic energy homeostasis. The ATPase EH domain-containing 2 (EHD2) has previously been shown to regulate caveolae, plasma membrane-specific domains that are involved in lipid uptake and signal transduction. Here, we investigated the role of EHD2 in adipocyte function. We demonstrate that EHD2 protein expression is highly up-regulated at the onset of triglyceride accumulation during adipocyte di ...[more]