Ontology highlight
ABSTRACT:
SUBMITTER: Mao H
PROVIDER: S-EPMC6725465 | biostudies-literature | 2005 Aug
REPOSITORIES: biostudies-literature
Mao Hua H Ferguson Tanya S TS Cibulsky Susan M SM Holmqvist Mats M Ding Chunming C Fei Hong H Levitan Irwin B IB
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050801 35
We have cloned and characterized mouse and human variants of MONaKA, a novel protein that interacts with and modulates the plasma membrane Na,K-ATPase. MONaKA was cloned based on its sequence homology to the Drosophila Slowpoke channel-binding protein dSlob, but mouse and human MONaKA do not bind to mammalian Slowpoke channels. At least two splice variants of MONaKA exist; the splicing is conserved perfectly between mouse and human, suggesting that it serves some important function. Both splice ...[more]