Ontology highlight
ABSTRACT:
SUBMITTER: Chang S
PROVIDER: S-EPMC6726441 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Chang Suchan S Kim Dan Hyo DH Jang Eun Young EY Yoon Seong Shoon SS Gwak Young Seob YS Yi Yoo Jung YJ Lee Jun Yeon JY Ahn Song Hee SH Kim Jin Mook JM Ryu Yeon-Hee YH Kim Seung-Nam SN Roh Hyo Sun HS Lee Mi-Young MY Kim Sang Chan SC Lee Bong Hyo BH Kim Hee Young HY Yang Chae Ha CH
Science advances 20190904 9
A withdrawal-associated impairment in β-endorphin neurotransmission in the arcuate nucleus (ARC) of the hypothalamus is associated with alcohol dependence characterized by a chronic relapsing disorder. Although acupuncture activates β-endorphin neurons in the ARC projecting to the nucleus accumbens (NAc), a role for ARC β-endorphin neurons in alcohol dependence and acupuncture effects has not been examined. Here, we show that acupuncture at Shenmen (HT7) points attenuates behavioral manifestatio ...[more]