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Trypanosoma cruzi infection in a zoo-housed red panda in Kansas.

ABSTRACT: A 9-y-old, zoo-housed, male red panda (Ailurus fulgens) became progressively lethargic and inappetent over a 1-wk period. Physical examination was unremarkable. A complete blood count showed mild normocytic, normochromic, non-regenerative anemia with the presence of trypomastigote organisms, consistent with a Trypanosoma sp. The organism was confirmed later as Trypanosoma cruzi lineage TcI via PCR and genome sequencing. The panda was initially treated supportively; however, its clinical status within 24?h from presentation deteriorated, and euthanasia was elected. Autopsy showed severe systemic T. cruzi infection with the presence of amastigotes in the heart, brain, peripheral nerves, skeletal muscles, tongue, liver, and testes. We used genome sequencing and serology in identifying the agent.

SUBMITTER: Huckins GL

PROVIDER: S-EPMC6727118 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Trypanosoma cruzi infection in a zoo-housed red panda in Kansas.

Huckins Gail L GL Eshar David D Schwartz Diana D Morton Mark M Herrin Brian H BH Cerezo Argine A Yabsley Michael J MJ Schneider Sarah M SM

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20190725 5

A 9-y-old, zoo-housed, male red panda (Ailurus fulgens) became progressively lethargic and inappetent over a 1-wk period. Physical examination was unremarkable. A complete blood count showed mild normocytic, normochromic, non-regenerative anemia with the presence of trypomastigote organisms, consistent with a Trypanosoma sp. The organism was confirmed later as Trypanosoma cruzi lineage TcI via PCR and genome sequencing. The panda was initially treated supportively; however, ...[more]

PMID: 31342874

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