Predicting Phenotypic Diversity from Molecular and Genetic Data.
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ABSTRACT:
SUBMITTER: Harel T
PROVIDER: S-EPMC6727812 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Predicting Phenotypic Diversity from Molecular and Genetic Data.
Harel Tom T Peshes-Yaloz Naama N Bacharach Eran E Gat-Viks Irit I
Genetics 20190727 1
Despite the importance of complex phenotypes, an in-depth understanding of the combined molecular and genetic effects on a phenotype has yet to be achieved. Here, we introduce InPhenotype, a novel computational approach for complex phenotype prediction, where gene-expression data and genotyping data are integrated to yield quantitative predictions of complex physiological traits. Unlike existing computational methods, InPhenotype makes it possible to model potential regulatory interactions betwe ...[more]
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