Ontology highlight
ABSTRACT:
SUBMITTER: Kim WJ
PROVIDER: S-EPMC6728082 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Cell host & microbe 20190801 2
The mucosa is colonized with commensal Neisseria. Some of these niches are sites of infection for the STD pathogen Neisseria gonorrhoeae (Ngo). Given the antagonistic behavior of commensal bacteria toward their pathogenic relatives, we hypothesized that commensal Neisseria may negatively affect Ngo colonization. Here, we report that commensal species of Neisseria kill Ngo through a mechanism based on genetic competence and DNA methylation state. Specifically, commensal-triggered killing occurs w ...[more]