Ontology highlight
ABSTRACT:
SUBMITTER: Huang LN
PROVIDER: S-EPMC6728171 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Huang Li-Na LN Zou Yun Y Wu Shao-Gen SG Zhang Hong-Hong HH Mao Qing-Xiang QX Li Jin-Bao JB Tao Yuan-Xiang YX
Molecular neurobiology 20190411 10
Fibroblast growth factor-inducible-14 (Fn14), a receptor for tumor necrosis-like weak inducer of apoptosis, is expressed in the neurons of dorsal root ganglion (DRG). Its mRNA is increased in the injured DRG following peripheral nerve injury. Whether this increase contributes to neuropathic pain is unknown. We reported here that peripheral nerve injury caused by spinal nerve ligation (SNL) increased the expression of Fn14 at both protein and mRNA levels in the injured DRG. Blocking this increase ...[more]