Ontology highlight
ABSTRACT:
SUBMITTER: Bu LL
PROVIDER: S-EPMC6728673 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Bu L L LL Yu G T GT Wu L L Mao L L Deng W W WW Liu J F JF Kulkarni A B AB Zhang W F WF Zhang L L Sun Z J ZJ
Journal of dental research 20170612 9
Head and neck cancer is one of the most prevalent cancers around the world. Head and neck squamous cell carcinoma (HNSCC) accounts for nearly 90% of head and neck cancer. In recent years, significant advances have been made in immunotherapy for HNSCC. Although some clinical trials targeting immune checkpoints have shown success, the molecular mechanism for regulation of programmed death 1 (PD-1) and its ligand (PD-L1) is partially understood. In an effort to explore the effect of activation of s ...[more]