Ontology highlight
ABSTRACT:
SUBMITTER: Bradt V
PROVIDER: S-EPMC6731309 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Bradt Victoria V Malafa Stefan S von Braun Amrei A Jarmer Johanna J Tsouchnikas Georgios G Medits Iris I Wanke Kerstin K Karrer Urs U Stiasny Karin K Heinz Franz X FX
NPJ vaccines 20190906
Flaviviruses have an increasing global impact as arthropod-transmitted human pathogens, exemplified by Zika, dengue, yellow fever (YF), West Nile, Japanese encephalitis, and tick-borne encephalitis (TBE) viruses. Since all flaviviruses are antigenically related, they are prone to phenomena of immunological memory ('original antigenic sin'), which can modulate immune responses in the course of sequential infections and/or vaccinations. In our study, we analyzed the influence of pre-existing YF va ...[more]