Ontology highlight
ABSTRACT:
SUBMITTER: Jacobs CT
PROVIDER: S-EPMC6733594 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
eLife 20190827
Spinal cord patterning is orchestrated by multiple cell signalling pathways. Neural progenitors are maintained by Notch signalling, whereas ventral neural fates are specified by Hedgehog (Hh) signalling. However, how dynamic interactions between Notch and Hh signalling drive the precise pattern formation is still unknown. We applied the PHRESH (<u>PH</u>otoconvertible <u>RE</u>porter of <u>S</u>ignalling <u>H</u>istory) technique to analyse cell signalling dynamics in vivo during zebrafish spina ...[more]