Ontology highlight
ABSTRACT:
SUBMITTER: Meek RW
PROVIDER: S-EPMC6733907 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Nature communications 20190909 1
The bacterial second messenger cyclic-di-GMP is a widespread, prominent effector of lifestyle change. An example of this occurs in the predatory bacterium Bdellovibrio bacteriovorus, which cycles between free-living and intraperiplasmic phases after entering (and killing) another bacterium. The initiation of prey invasion is governed by DgcB (GGDEF enzyme) that produces cyclic-di-GMP in response to an unknown stimulus. Here, we report the structure of DgcB, and demonstrate that the GGDEF and sen ...[more]