Ontology highlight
ABSTRACT:
SUBMITTER: Deng J
PROVIDER: S-EPMC6735535 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Deng Juan J Zhao Sha S Zhang Xiaoshen X Jia Keyi K Wang Hao H Zhou Caicun C He Yayi Y
OncoTargets and therapy 20190906
Immunotherapy has shown promising results in cancer treatment. Research shows that most patients might be resistant to these therapies. So, new immune therapies are needed. OX40 (CD134) and OX40 ligand (OX40L), costimulatory molecules, express on different types of immune cells. The interaction between OX40 and OX40L (OX40/OX40L) induces the expansion and proliferation of T cells and decreases the immunosuppression of regulatory T (Treg) cells to enhance the immune response to the specific antig ...[more]