Ensembldb: an R package to create and use Ensembl-based annotation resources.

ABSTRACT: SUMMARY:Bioinformatics research frequently involves handling gene-centric data such as exons, transcripts, proteins and their positions relative to a reference coordinate system. The ensembldb Bioconductor package retrieves and stores Ensembl-based genetic annotations and positional information, and furthermore offers identifier conversion and coordinates mappings for gene-associated data. In support of reproducible research, data are tied to Ensembl releases and are kept separately from the software. Premade data packages are available for a variety of genomes and Ensembl releases. Three examples demonstrate typical use cases of this software. AVAILABILITY AND IMPLEMENTATION:ensembldb is part of Bioconductor (https://bioconductor.org/packages/ensembldb). SUPPLEMENTARY INFORMATION:Supplementary data are available at Bioinformatics online.

SUBMITTER: Rainer J 

PROVIDER: S-EPMC6736197 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature