Decontamination and management of contaminated hair following a CBRN incident.

ABSTRACT: This in vitro study evaluated the "triple protocol" of dry decontamination, the ladder pipe system, a method for gross decontamination, and technical decontamination in the decontamination of hair following chemical contamination. First, we assessed the efficacy of the three protocols, alone or in combination, on excised porcine skin and human hair contaminated with either methyl salicylate (MS), phorate (PHR), sodium fluoroacetate (SFA) or potassium cyanide (KCN). A second experiment investigated the residual hair contamination following decontamination with the triple protocol at different intervals post exposure. In a third experiment, hair decontaminated after exposure to MS or PHR was evaluated for off-gassing. Though skin decontamination was highly effective, a substantial proportion (20-40%) of the lipophilic compounds (MS and PHR) remained within the hair. The more water-soluble contaminants (SFA and KCN) tended to form much smaller reservoirs within the hair. Interestingly, substantial off-gassing of MS, a medium volatility chemical, was detectable from triple-decontaminated hair up to five days post exposure. Overall, the decontamination strategies investigated were effective for the decontamination of skin, but less so for hair. These findings highlight the importance of contaminated hair serving as a source of potential secondary contamination by contact or inhalation. Therefore, consideration should be given to the management of contaminated hair following exposure to toxic chemicals.

SUBMITTER: Matar H 

PROVIDER: S-EPMC6736418 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature