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Developing an optimal short-form of the PTSD Checklist for DSM-5 (PCL-5).


ABSTRACT: BACKGROUND:Although several short-forms of the posttraumatic stress disorder (PTSD) Checklist (PCL) exist, all were developed using heuristic methods. This report presents the results of analyses designed to create an optimal short-form PCL for DSM-5 (PCL-5) using both machine learning and conventional scale development methods. METHODS:The short-form scales were developed using independent datasets collected by the Army Study to Assess Risk and Resilience among Service members. We began by using a training dataset (n?=?8,917) to fit short-form scales with between 1 and 8 items using different statistical methods (exploratory factor analysis, stepwise logistic regression, and a new machine learning method to find an optimal integer-scored short-form scale) to predict dichotomous PTSD diagnoses determined using the full PCL-5. A smaller subset of best short-form scales was then evaluated in an independent validation sample (n?=?11,728) to select one optimal short-form scale based on multiple operating characteristics (area under curve [AUC], calibration, sensitivity, specificity, net benefit). RESULTS:Inspection of AUCs in the training sample and replication in the validation sample led to a focus on 4-item integer-scored short-form scales selected with stepwise regression. Brier scores in the validation sample showed that a number of these scales had comparable calibration (0.015-0.032) and AUC (0.984-0.994), but that one had consistently highest net benefit across a plausible range of decision thresholds. CONCLUSIONS:The recommended 4-item integer-scored short-form PCL-5 generates diagnoses that closely parallel those of the full PCL-5, making it well-suited for screening.

SUBMITTER: Zuromski KL 

PROVIDER: S-EPMC6736721 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Developing an optimal short-form of the PTSD Checklist for DSM-5 (PCL-5).

Zuromski Kelly L KL   Ustun Berk B   Hwang Irving I   Keane Terence M TM   Marx Brian P BP   Stein Murray B MB   Ursano Robert J RJ   Kessler Ronald C RC  

Depression and anxiety 20190729 9


<h4>Background</h4>Although several short-forms of the posttraumatic stress disorder (PTSD) Checklist (PCL) exist, all were developed using heuristic methods. This report presents the results of analyses designed to create an optimal short-form PCL for DSM-5 (PCL-5) using both machine learning and conventional scale development methods.<h4>Methods</h4>The short-form scales were developed using independent datasets collected by the Army Study to Assess Risk and Resilience among Service members. W  ...[more]

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