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Association between hand grip strength and impaired health-related quality of life in Korean cancer survivors: a cross-sectional study.

ABSTRACT: OBJECTIVES:To assess the association between hand grip strength (HGS) and health-related quality of life (HRQoL) among Korean cancer survivors. DESIGN:Population-based cross-sectional study. SETTING:A nationally representative population survey data (face-to-face interviews and health examinations were performed in mobile examination centres). PARTICIPANTS:A total of 1037 cancer survivors (person with cancer of any type who is still living) with available data on HGS and HRQoL in the sixth and seventh Korea National Health and Nutrition Examination Surveys (2014-2017). PRIMARY OUTCOME MEASURES:Prevalence of impaired HRQoL by HGS. RESULTS:Among 1037 cancer survivors (60.7% women, mean age=62.2 years), 19.2% of them had weak HGS according to gender-specific cut-off values (lowest quintile<29.7?kg in men and <19.7?kg in women). In the study population, the most common cancer site was the stomach, followed by the thyroid, breast, colorectal and cervix. Individuals with weak HGS showed statistically significantly increased impairment in all five dimensions of the EuroQoL-5 dimension (EQ-5D) compared with those in patients with normal HGS. In a multinomial logistic regression analysis, impaired HRQoL (some or extreme problem in EQ-5D) was significantly reduced in each dimension of the EQ-5D, except for anxiety/depression, when HGS was increased. The OR for impaired HRQoL ranged from 0.86 to 0.97 per 1?kg increase in HGS in four dimensions (mobility, self-care, usual activity and pain/discomfort). CONCLUSIONS:Weak HGS was associated with impaired HRQoL in cancer survivors. Future longitudinal studies are needed to confirm the causality between HGS and HRQoL in cancer survivors.

SUBMITTER: Paek J

PROVIDER: S-EPMC6738715 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Association between hand grip strength and impaired health-related quality of life in Korean cancer survivors: a cross-sectional study.

Paek Jeongki J Choi Yoon Ji YJ

BMJ open 20190908 9

<h4>Objectives</h4>To assess the association between hand grip strength (HGS) and health-related quality of life (HRQoL) among Korean cancer survivors.<h4>Design</h4>Population-based cross-sectional study.<h4>Setting</h4>A nationally representative population survey data (face-to-face interviews and health examinations were performed in mobile examination centres).<h4>Participants</h4>A total of 1037 cancer survivors (person with cancer of any type who is still living) with available data on HGS ...[more]

PMID: 31501128

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Project description:BackgroundPregnancy results in many changes, including reduced hand grip strength (HGS). However, good HGS is required for physical functions such as carrying and breastfeeding the baby after birth. The aim of this study was to determine the factors that may predict HGS during pregnancy.MethodsThe study was a cross-sectional study approved by the Research Ethics Committees of Kano State Ministry of Health and Aminu Kano Teaching Hospital in Kano, north-west, Nigeria. Pregnant women at the designated hospitals were included in the study if they had no serious comorbidities or any known neurological condition that affects the hands and the neck. Demographic characteristics and independent (predictor) variables (age, weight, height, BMI, maternity leave status, number of full-term deliveries, number of preterm deliveries, number of live births, number of abortuses, gravidity, trimester, systolic blood pressure, diastolic blood pressure, inter arm systolic BP difference [IASBP], inter arm diastolic BP difference [IADBP], and heart rate) of each of the participants were recorded by experienced therapists. The data were analysed using descriptive statistics, t-test, Pearson correlation coefficient and standard multiple regression.ResultOne hundred and sixty-one pregnant women with mean age, 25.04 ± 4.83 years participated in the study. In the dominant hand, 120 participants (74.5%) had weak grip strength. In the non-dominant hand, 135 participants (83.9%) had weak grip strength. For the dominant hand, the total variance explained by the whole model was significant, 28.5%, F(11, 161) = 1.187, R2 = 0.081, p = 0.300 . In the final model, none of the variables significantly predicted HGS. However, systolic blood pressure contributed to the model more than any other variable (Beta = -0.155). For the non-dominant hand, the total variance explained by the whole model was not significant, 33.1%, F(11, 161) = 1.675, R2 = 0.111, p = 0.089 . In the final model, only systolic blood pressure (Beta = -0.254, p = 0.023) significantly predicted hand grip strength.ConclusionCardiovascular events or changes during pregnancy (such as change in systolic blood pressure) may be related to HGS in pregnant women. It is therefore, important for clinicians to pay attention to this, in planning rehabilitation strategies for pregnant women.

Dataset Information

Association between hand grip strength and impaired health-related quality of life in Korean cancer survivors: a cross-sectional study.

Publications

Association between hand grip strength and impaired health-related quality of life in Korean cancer survivors: a cross-sectional study.

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