Ontology highlight
ABSTRACT:
SUBMITTER: Moccia R
PROVIDER: S-EPMC6740582 | biostudies-literature | 2003 Oct
REPOSITORIES: biostudies-literature
Moccia Robert R Chen Dillon D Lyles Vlasta V Kapuya Estreya E E Yaping Y Kalachikov Sergey S Spahn Christian M T CM Frank Joachim J Kandel Eric R ER Barad Mark M Martin Kelsey C KC
The Journal of neuroscience : the official journal of the Society for Neuroscience 20031001 28
Local protein synthesis is required for long-lasting synapse-specific plasticity in cultured Aplysia sensorimotor synapses. To identify synaptically localized mRNAs, we prepared a cDNA library from isolated sensory neurites. By sequence analysis, we estimate that the library contains 263 distinct mRNAs, with 98 of these mRNAs constituting 70% of all clones. The localized transcripts are enriched for mRNAs encoding cytoskeletal elements and components of the translational machinery. In situ hybri ...[more]