Ontology highlight
ABSTRACT:
SUBMITTER: Watanabe S
PROVIDER: S-EPMC6741582 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Watanabe Shinichiro S Noma Kazuhiro K Ohara Toshiaki T Kashima Hajime H Sato Hiroaki H Kato Takuya T Urano Shinichi S Katsube Ryoichi R Hashimoto Yuuri Y Tazawa Hiroshi H Kagawa Shunsuke S Shirakawa Yasuhiro Y Kobayashi Hisataka H Fujiwara Toshiyoshi T
Cancer biology & therapy 20190611 9
Cancer-associated fibroblasts (CAFs) are strongly implicated in tumor progression, including in the processes of tumorigenesis, invasion, and metastasis. The targeting of CAFs using various therapeutic approaches is a novel treatment strategy; however, the efficacy of such therapies remains limited. Recently, near-infrared photoimmunotherapy (NIR-PIT), which is a novel targeted therapy employing a cell-specific mAb conjugated to a photosensitizer, has been introduced as a new type of phototherap ...[more]