Ontology highlight
ABSTRACT:
SUBMITTER: Saba R
PROVIDER: S-EPMC6742033 | biostudies-literature | 2003 Mar
REPOSITORIES: biostudies-literature
Saba Rie R Nakatsuji Norio N Saito Tetsuichiro T
The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301 6
Commissural neurons in the spinal cord project their axons through the floor plate using a number of molecular interactions, such as netrins and their receptor DCC (deleted in colorectal cancer). However, the molecular cascades that control differentiation of commissural neurons are less characterized. A homeobox gene, MBH1 (mammalian BarH1) was expressed specifically in a subset of dorsal cells in the developing spinal cord. Transgenic mice that carried lacZ and MBH1-flanking genome sequences d ...[more]