Ontology highlight
ABSTRACT:
SUBMITTER: Bi J
PROVIDER: S-EPMC6742496 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Bi Junfeng J Ichu Taka-Aki TA Zanca Ciro C Yang Huijun H Zhang Wei W Gu Yuchao Y Chowdhry Sudhir S Reed Alex A Ikegami Shiro S Turner Kristen M KM Zhang Wenjing W Villa Genaro R GR Wu Sihan S Quehenberger Oswald O Yong William H WH Kornblum Harley I HI Rich Jeremy N JN Cloughesy Timothy F TF Cavenee Webster K WK Furnari Frank B FB Cravatt Benjamin F BF Mischel Paul S PS
Cell metabolism 20190711 3
Advances in DNA sequencing technologies have reshaped our understanding of the molecular basis of cancer, providing a precise genomic view of tumors. Complementary biochemical and biophysical perspectives of cancer point toward profound shifts in nutrient uptake and utilization that propel tumor growth and major changes in the structure of the plasma membrane of tumor cells. The molecular mechanisms that bridge these fundamental aspects of tumor biology remain poorly understood. Here, we show th ...[more]