Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays.
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ABSTRACT:
SUBMITTER: Bullmann T
PROVIDER: S-EPMC6742744 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays.
Bullmann Torsten T Radivojevic Milos M Huber Stefan T ST Deligkaris Kosmas K Hierlemann Andreas A Frey Urs U
Frontiers in cellular neuroscience 20190906
Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but there is still a need for methods to investigate full axonal arbors at sufficient throughput. Here, we present a new method for the simultaneous mapping of the axonal arbors of a large number of individual neurons, which relies on their extracellul ...[more]
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