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Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation.


ABSTRACT: Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the body, and clinically available imaging tools lack specificity. New approaches are needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments and can provide key information about infectious processes deep within the body.

SUBMITTER: Ordonez AA 

PROVIDER: S-EPMC6743081 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation.

Ordonez Alvaro A AA   Sellmyer Mark A MA   Gowrishankar Gayatri G   Ruiz-Bedoya Camilo A CA   Tucker Elizabeth W EW   Palestro Christopher J CJ   Hammoud Dima A DA   Jain Sanjay K SK  

Science translational medicine 20190901 508


Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the body, and clinically available imaging tools lack specificity. New approaches are needed for early diagnosis and monitoring of bacterial infections and rapid detection of drug-resistant organisms. Molecular imaging allows for longitudinal, noninvasive assessments and can provide key information about infectious processes deep within the body. ...[more]

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