Ontology highlight
ABSTRACT:
SUBMITTER: Zhang J
PROVIDER: S-EPMC6744288 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Zhang Jing J Kinch Lisa N LN Cong Qian Q Katsonis Panagiotis P Lichtarge Olivier O Savojardo Castrense C Babbi Giulia G Martelli Pier Luigi PL Capriotti Emidio E Casadio Rita R Garg Aditi A Pal Debnath D Weile Jochen J Sun Song S Verby Marta M Roth Frederick P FP Grishin Nick V NV
Human mutation 20190903 9
This paper reports the evaluation of predictions for the "CALM1" challenge in the fifth round of the Critical Assessment of Genome Interpretation held in 2018. In the challenge, the participants were asked to predict effects on yeast growth caused by missense variants of human calmodulin, a highly conserved protein in eukaryotic cells sensing calcium concentration. The performance of predictors implementing different algorithms and methods is similar. Most predictors are able to identify the del ...[more]