Ontology highlight
ABSTRACT:
SUBMITTER: Albarino CG
PROVIDER: S-EPMC6745713 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Albariño César G CG Guerrero Lisa Wiggleton LW Chakrabarti Ayan K AK Kainulainen Markus H MH Whitmer Shannon L M SLM Welch Stephen R SR Nichol Stuart T ST
Virology 20160629
During the large outbreak of Ebola virus disease that occurred in Western Africa from late 2013 to early 2016, several hundred Ebola virus (EBOV) genomes have been sequenced and the virus genetic drift analyzed. In a previous report, we described an efficient reverse genetics system designed to generate recombinant EBOV based on a Makona variant isolate obtained in 2014. Using this system, we characterized the replication and fitness of 2 isolates of the Makona variant. These virus isolates are ...[more]