Ontology highlight
ABSTRACT:
SUBMITTER: Chen W
PROVIDER: S-EPMC6746239 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Chen Wei W Cheng Chi-An CA Cosco Emily D ED Ramakrishnan Shyam S Lingg Jakob G P JGP Bruns Oliver T OT Zink Jeffrey I JI Sletten Ellen M EM
Journal of the American Chemical Society 20190802 32
Tissue is translucent to shortwave infrared (SWIR) light, rendering optical imaging superior in this region. However, the widespread use of optical SWIR imaging has been limited, in part, by the lack of bright, biocompatible contrast agents that absorb and emit light above 1000 nm. J-Aggregation offers a means to transform stable, near-infrared (NIR) fluorophores into red-shifted SWIR contrast agents. Here we demonstrate that J-aggregates of NIR fluorophore IR-140 can be prepared inside hollow m ...[more]