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Implications of Chronic Opioid Therapy on Perioperative Complications and Long-Term Surgical Recovery.

ABSTRACT: With chronic opioid use becoming an increasingly common occurrenceamong the general population, perioperative specialties must adapt to the physiologic changes caused by long-term opioids. However, data on the clinicalanesthetics implications of long-term opioid use is scarce. This review intends to survey the literature addressing the molecular mechanisms of long-term opioid use as well as their interaction with various organ systems.

SUBMITTER: Liu D 

PROVIDER: S-EPMC6746432 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Implications of Chronic Opioid Therapy on Perioperative Complications and Long-Term Surgical Recovery.

Liu Da D   DiMeglio Matthew M   DiMartino Michael M   Hajj Jihane J   Mukhanova Maria M   Rai Karima K   Winikor Mazell M   Laudanski Krzysztof K  

Translational perioperative and pain medicine 20190829 4

With chronic opioid use becoming an increasingly common occurrenceamong the general population, perioperative specialties must adapt to the physiologic changes caused by long-term opioids. However, data on the clinicalanesthetics implications of long-term opioid use is scarce. This review intends to survey the literature addressing the molecular mechanisms of long-term opioid use as well as their interaction with various organ systems. ...[more]