Ontology highlight
ABSTRACT:
SUBMITTER: Markofski MM
PROVIDER: S-EPMC6748753 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Markofski Melissa M MM Jennings Kristofer K Timmerman Kyle L KL Dickinson Jared M JM Fry Christopher S CS Borack Michael S MS Reidy Paul T PT Deer Rachel R RR Randolph Amanda A Rasmussen Blake B BB Volpi Elena E
The journals of gerontology. Series A, Biological sciences and medical sciences 20190901 10
<h4>Background</h4>Essential amino acids (EAA) and aerobic exercise (AE) acutely and independently stimulate skeletal muscle protein anabolism in older adults.<h4>Objective</h4>In this Phase 1, double-blind, placebo-controlled, randomized clinical trial, we determined if chronic EAA supplementation, AE training, or a combination of the two interventions could improve muscle mass and function by stimulating muscle protein synthesis.<h4>Methods</h4>We phone-screened 971, enrolled 109, and randomiz ...[more]