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G4Hunter web application: a web server for G-quadruplex prediction.

ABSTRACT: MOTIVATION:Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. RESULTS:We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. AVAILABILITY AND IMPLEMENTATION:G4Hunter web application can be accessed at: http://bioinformatics.ibp.cz. SUPPLEMENTARY INFORMATION:Supplementary data are available at Bioinformatics online.

SUBMITTER: Brazda V

PROVIDER: S-EPMC6748775 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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G4Hunter web application: a web server for G-quadruplex prediction.

Brázda Václav V Kolomazník Jan J Lýsek Jiří J Bartas Martin M Fojta Miroslav M Šťastný Jiří J Mergny Jean-Louis JL

Bioinformatics (Oxford, England) 20190901 18

<h4>Motivation</h4>Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community.<h4>Results</h4>We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete ...[more]

PMID: 30721922

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