Ontology highlight
ABSTRACT:
SUBMITTER: Galinovic I
PROVIDER: S-EPMC6749039 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Galinovic Ivana I Boutitie Florent F Fiebach Jochen B JB Villringer Kersten K Cheng Bastian B Ebinger Martin M Endres Matthias M Fiehler Jens J Ford Ian I Thijs Vincent V Lemmens Robin R Muir Keith W KW Nighoghossian Norbert N Pedraza Salvador S Simonsen Claus Z CZ Roy Pascal P Gerloff Christian C Thomalla Götz G
Frontiers in neurology 20190911
<b>Introduction:</b> In WAKE-UP (Efficacy and Safety of MRI-based Thrombolysis in Wake-Up Stroke), patients with an acute stroke of unknown onset time were randomized to treatment with intravenous alteplase or placebo, guided by MRI. <b>Methods:</b> In this exploratory <i>post-hoc</i> secondary analysis we compared clinical and imaging data, as well as treatment effects and safety of intravenous thrombolysis between patients with infra- vs. supratentorial stroke. <b>Results:</b> Forty-eight out ...[more]