Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Development of Azo-Based Turn-On Chemical Array System for Hydrazine Detection with Fluorescence Pattern Analysis.

ABSTRACT: A facile turn-on chemical sensor array was developed for hydrazine detection by means of fluorescence pattern recognition. Taking advantage of the unique properties of the azo group, four different fluorogenic probes, Seoul-Fluor (SF)-Azo 01-04, were designed and prepared. SF-Azo 01-04 displayed fluorescence enhancement of up to 800-fold upon reaction with hydrazine, and all probes exhibited excellent selectivity in the presence of various anions and nucleophiles. By employing the probes in a cellulose paper-based array system, the hydrazine concentration was successfully determined by monitoring the change in fluorescent patterns.

SUBMITTER: Shin MC

PROVIDER: S-EPMC6751537 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Development of Azo-Based Turn-On Chemical Array System for Hydrazine Detection with Fluorescence Pattern Analysis.

Shin Min Chul MC Lee Youngjun Y Park Seung Bum SB Kim Eunha E

ACS omega 20190903 12

A facile turn-on chemical sensor array was developed for hydrazine detection by means of fluorescence pattern recognition. Taking advantage of the unique properties of the azo group, four different fluorogenic probes, Seoul-Fluor (SF)-Azo 01-04, were designed and prepared. SF-Azo 01-04 displayed fluorescence enhancement of up to 800-fold upon reaction with hydrazine, and all probes exhibited excellent selectivity in the presence of various anions and nucleophiles. By ...[more]

PMID: 31552327

Similar Datasets

"Turn-Off" Supramolecular Fluorescence Array Sensor for Heavy Metal Ion Identification.

Project description:A "turn-off" supramolecular fluorescence array sensor based on the host-guest complexes between fluorescence dyes and cucurbit[n]urils for sensing metal ions was developed. Three fluorescent probes (RhB@Q[7], H33342@2Q[7], and BRE@Q[7]) were used as the sensing units to construct a supramolecular fluorescence array sensor. The binding ability of the metal ions and cucurbituril-dye probes varied; therefore, the probes and metal ions produced different fluorescence responses. When combined with linear discriminant analysis (LDA), the qualitative and quantitative detection of seven metal ions was achieved. In analytical samples, the supramolecular fluorescence array sensor recognized and distinguish seven metal ions. These results provided new research ideas for the rapid analysis and real-time monitoring of different heavy metal ions.

| S-EPMC8613849 | biostudies-literature

π-Extended Tetraphenylethylene Containing a Dicyanovinyl Group as an Ideal Fluorescence Turn-On and Naked-Eye Color Change Probe for Hydrazine Detection.

Project description:A π-extended tetraphenylethylene derivative 1 was developed as a fluorescent "turn-on" and "naked-eye" color change probe for hydrazine detection. Probe 1 was composed of the representative AIE luminogen (AIEgen), tetraphenylethylene, and a dicyanovinyl group was adopted for hydrazine recognition. Upon exposure of hydrazine, probe 1 immediately gave a significant aggregation-induced emission around 575 nm and excellent photostability. A naked-eye color change was also observed from red to yellow. Moreover, probe 1 was simply coated with a glass-backed silica gel-coated thin-layer chromatography plate, showing rapid and on-site detection of hydrazine vapor.

| S-EPMC7643319 | biostudies-literature

Fluorescence turn on amine detection in a cationic covalent organic framework.

Project description:Ionic covalent organic frameworks (iCOFs) are new examples of porous materials and have shown great potential for various applications. When functionalized with suitable emission sites, guest uptake via the ionic moieties of iCOFs can cause a significant change in luminescence, making them excellent candidates for chemosensors. In here, we present a luminescence sensor in the form of an ionic covalent organic framework (TGH+•PD) composed of guanidinium and phenanthroline moieties for the detection of ammonia and primary aliphatic amines. TGH+•PD exhibits strong emission enhancement in the presence of selective primary amines due to the suppression of intramolecular charge transfer (ICT) with an ultra-low detection limit of 1.2 × 10‒7 M for ammonia. The presence of ionic moieties makes TGH+•PD highly dispersible in water, while deprotonation of the guanidinium moiety by amines restricts its ICT process and signals their presence by enhanced fluorescence emission. The presence of ordered pore walls introduces size selectivity among analyte molecules, and the iCOF has been successfully used to monitor meat products that release biogenic amine vapors upon decomposition due to improper storage.

| S-EPMC9263141 | biostudies-literature

Tailoring of the desired selectivity and the turn-on detection range in a self-assembly-based fluorescence sensory system.

Project description:This study demonstrates how to control the selectivity and the turn-on detection range toward the tailoring of an assembly-based fluorescence (FL) sensory system. Assembly-based FL chemosensors composed of oligophenylenevinylene with a varied number of guanidinium receptors (G2, G4 and G6) were newly developed, and their FL response to nucleotides (AMP, ADP and ATP) was investigated. Indeed, G6 exhibited FL emission via self-assembly with ATP. More importantly, the FL response of G6 showed markedly improved selectivity for ATP over ADP and a broadly extended detection range of ATP concentration under adjusted salt conditions. The salt effect on the FL response revealed the competitive binding interactions affecting the subsequent self-assembly process. These studies have unveiled the pivotal binding mechanisms operating in the self-assembly process, which tailor the performance level of the assembly-based sensory system. We believe that this study offers a new design principle of an assembly-based FL chemosensor with high selectivity and the appropriate detection range, being different from the conventional key-and-lock system.

| S-EPMC5707478 | biostudies-literature

A Metallosupramolecular Coordination Polymer for the 'Turn-on' Fluorescence Detection of Hydrogen Sulfide.

Project description:A coumarin based probe for the efficient detection of hydrogen sulfide in aqueous medium is reported. The investigated coumarine-based derivative forms spherical nanoparticles in aqueous media. In presence of Pd2+, a metallosupramolecular coordination polymer is formed, which is accompanied by quenching of the coumarin emission at 390 nm. Its Pd2+ complex could be used as a probe for chemoselective detection of monohydrogensulfide (HS-). Presence of HS- leads to a'turn-on' fluorescence signal, resulting from decomplexation of Pd2+ from the metallosupramolecular probe. The probe was successfully applied for qualitative and quantitative detection of HS- in different sources of water directly collected from sea, river, tap and laboratory drain water, as well as in growth media for aquatic species.

| S-EPMC7391242 | biostudies-literature

Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift.

Project description:Diethyl malonate-based fluorescent probe NE-N 2 H 4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N 2 H 4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N 2 H 4 can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N 2 H 4 might be used to monitor hydrazine in biosamples and environmental problem.

| S-EPMC8012553 | biostudies-literature

Micro-optical lens array for fluorescence detection in droplet-based microfluidics.

Project description:We demonstrate the design and integration of droplet-based microfluidic devices with microoptical element arrays for enhanced detection of fluorescent signals. We show that the integration of microlenses and mirror surfaces in these devices results in an 8-fold increase in the fluorescence signal and in improved spatial resolution. Using an array of microlenses, massively parallel detection of droplets containing fluorescent dyes was achieved, leading to detection throughputs of about 2000 droplets per second and per lens, parallelized over 625 measurement points.

| S-EPMC3697795 | biostudies-literature

A Mononuclear Zinc Complex for Selective Detection of Diphosphate via Fluorescence ESIPT Turn-On.

Project description:A mononuclear zinc complex has been found to exhibit unexpected selectivity for biologically important diphosphate anions (PPi and ADP). The diphosphate binding could turn-on the ESIPT, whose study reveals mechanistic insight to aid the future design of new sensors.

| S-EPMC4077332 | biostudies-literature

Fluorescence detection of FAO activity with a chemical probe in cultured cells and mouse liver tissue

Project description:Fatty acid beta oxidation (FAO) pathway is an important metabolic pathway for energy generation and is deeply associated with various diseases such as cancer and NAFLD/NASH. Therefore, development of detection methods of FAO activity change would contribute to understanding of disease mechanism and drug discovery. In this study, we newly developed a fluorescent probe for fluorescence detection of FAO activity in cultured cells and mouse liver tissue and applied this probe for investigation of the heterogeneity of FAO activity in mouse liver tissue by FACS and mRNA sequence.

2023-02-15 | GSE224649 | GEO

A Selective Fluorescence Turn-On Probe for the Detection of DCNP (Nerve Agent Tabun Simulant).

Project description:Diethylcyanophosphonate (DCNP) is a simulant of Tabun (GA) which is an extremely toxic chemical substance and is used as a chemical warfare (CW) nerve agent. Due to its toxic properties, monitoring methods have been constantly come under the spotlight. What we are proposing within this report is a next-generation fluorescent probe, DMHN1, which allows DCNP to become fully traceable in a sensitive, selective, and responsive manner. This is the first fluorescent turn-on probe within the dipolar naphthalene platform induced by ESIPT (excited state intramolecular proton transfer) suppression that allows us to sense DCNP without any disturbance by other similar G-series chemical weapons. The successful demonstrations of practical applications, such as in vitro analysis, soil analysis, and the development of an on-site real-time prototype sensing kit, encourage further applications in a variety of fields.

| S-EPMC6766206 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data