Dataset Information

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects.

ABSTRACT:

Background

Quantification of abdominal muscle mass by cross-sectional imaging has been increasingly used to diagnose sarcopenia; however, the technical method for quantification has not been standardized yet. We aimed to determine an optimal method to measure the abdominal muscle area.

Methods

Among 50 consecutive subjects who underwent abdominal CT and MRI for possible liver donation, total abdominal muscle area (TAMA) and total psoas muscle area (TPA) at the L3 inferior endplate level were measured by two blinded readers. Inter-scan agreement between CT and MRI and inter-reader agreement between the two readers were evaluated using intraclass correlation coefficient (ICC) and within-subject coefficient of variation (WSCV). To evaluate the effect of measurement level, one reader measured TAMA and TPA at six levels from the L2 to L4 vertebral bodies.

Results

TAMA was a more reliable biomarker than TPA in terms of inter-scan agreement (ICC: 0.928 vs. 0.788 for reader 1 and 0.853 vs. 0.821 for reader 2, respectively; WSCV: 8.3% vs. 23.4% for reader 1 and 10.4% vs. 22.3% for reader 2, respectively) and inter-reader agreement (ICC: 0.986 vs. 0.886 for CT and 0.865 vs. 0.669 for MRI, respectively; WSCV: 8.2% vs. 16.0% for CT and 11.6% vs. 29.7% for MRI, respectively). In terms of the measurement level, TAMA did not differ from the L2inf to L4inf levels, whereas TPA increased with a decrease in measurement level.

Conclusions

TAMA is a better biomarker than TPA in terms of inter-scan and inter-reader agreement and robustness to the measurement level. CT was a more reliable imaging modality than MRI. Our results support the use of TAMA measured by CT as a standard biomarker for abdominal muscle area measurement.

SUBMITTER: Park J

PROVIDER: S-EPMC6752777 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects.

Park Jisuk J Gil Jea Ryung JR Shin Youngbin Y Won Sang Eun SE Huh Jimi J You Myung-Won MW Park Hyo Jung HJ Sung Yu Sub YS Kim Kyung Won KW

PloS one 20190919 9

<h4>Background</h4>Quantification of abdominal muscle mass by cross-sectional imaging has been increasingly used to diagnose sarcopenia; however, the technical method for quantification has not been standardized yet. We aimed to determine an optimal method to measure the abdominal muscle area.<h4>Methods</h4>Among 50 consecutive subjects who underwent abdominal CT and MRI for possible liver donation, total abdominal muscle area (TAMA) and total psoas muscle area (TPA) at the L3 inferior endplate ...[more]

PMID: 31536542

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Dataset Information

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects.

Background

Methods

Results

Conclusions

Publications

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects.

Similar Datasets

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