Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis.
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ABSTRACT:
SUBMITTER: Niu X
PROVIDER: S-EPMC6753331 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Functional Regulation of Macrophage Phenotypes by MicroRNAs in Inflammatory Arthritis.
Niu Xiaoling X Schulert Grant S GS
Frontiers in immunology 20190913
Inflammatory arthritis including rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) exhibit the shared feature of changes in activation and polarization of circulating monocytes and tissue macrophages. Numerous microRNAs (miRs) have been found to have key functions in regulating inflammation and macrophage polarization. Although there is increasing interest in the roles of miRs in both RA and JIA, less is known regarding how miRs relate to functional properties of immune cells, in ...[more]
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