Ontology highlight
ABSTRACT:
SUBMITTER: Chapman CH
PROVIDER: S-EPMC6753361 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Chapman Christopher H CH Hara Jared H JH Molinaro Annette M AM Clarke Jennifer L JL Oberheim Bush Nancy Ann NA Taylor Jennie W JW Butowski Nicholas A NA Chang Susan M SM Fogh Shannon E SE Sneed Penny K PK Nakamura Jean L JL Raleigh David R DR Braunstein Steve E SE
Neuro-oncology practice 20190412 5
<h4>Background</h4>Optimal techniques and patient selection for salvage reirradiation of high-grade glioma (HGG) are unclear. In this study, we identify prognostic factors for freedom from progression (FFP) and overall survival (OS) after reirradiation, risk factors for high-grade toxicity, and validate clinical prognostic scores.<h4>Methods</h4>A total of 116 patients evaluated between 2000 and 2018 received reirradiation for HGG (99 WHO grade IV, 17 WHO grade III). Median time to first progres ...[more]