The clinical value of the patient-reported multiple sclerosis neuropsychological screening questionnaire.

ABSTRACT: BACKGROUND:Cognitive problems are difficult to identify in patients with multiple sclerosis (MS). OBJECTIVE:To investigate the clinical applicability of the patient-reported MS Neuropsychological Screening Questionnaire (MSNQ-P). METHODS:Cut-off scores were determined to differentiate between cognitively impaired (n?=?90), mildly cognitively impaired (n?=?115), and cognitively preserved (n?=?147) MS patients using receiver operating characteristic analyses. RESULTS:We could not define specific and sensitive cut-off scores. Higher scores (?27) did indicate cognitive impairment. Among patients with a higher education, lower scores (<12) indicated intact cognition. CONCLUSION:Certain scores can indicate intact or impaired cognitive function. Still, MSNQ-P scores should be interpreted with caution.

SUBMITTER: Nauta IM 

PROVIDER: S-EPMC6753646 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature