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The clinical value of the patient-reported multiple sclerosis neuropsychological screening questionnaire.


ABSTRACT: BACKGROUND:Cognitive problems are difficult to identify in patients with multiple sclerosis (MS). OBJECTIVE:To investigate the clinical applicability of the patient-reported MS Neuropsychological Screening Questionnaire (MSNQ-P). METHODS:Cut-off scores were determined to differentiate between cognitively impaired (n?=?90), mildly cognitively impaired (n?=?115), and cognitively preserved (n?=?147) MS patients using receiver operating characteristic analyses. RESULTS:We could not define specific and sensitive cut-off scores. Higher scores (?27) did indicate cognitive impairment. Among patients with a higher education, lower scores (<12) indicated intact cognition. CONCLUSION:Certain scores can indicate intact or impaired cognitive function. Still, MSNQ-P scores should be interpreted with caution.

SUBMITTER: Nauta IM 

PROVIDER: S-EPMC6753646 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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The clinical value of the patient-reported multiple sclerosis neuropsychological screening questionnaire.

Nauta Ilse M IM   Balk Lisanne J LJ   Sonder Judith M JM   Hulst Hanneke E HE   Uitdehaag Bernard Mj BM   Fasotti Luciano L   de Jong Brigit A BA  

Multiple sclerosis (Houndmills, Basingstoke, England) 20180518 11


<h4>Background</h4>Cognitive problems are difficult to identify in patients with multiple sclerosis (MS).<h4>Objective</h4>To investigate the clinical applicability of the patient-reported MS Neuropsychological Screening Questionnaire (MSNQ-P).<h4>Methods</h4>Cut-off scores were determined to differentiate between cognitively impaired (<i>n</i> = 90), mildly cognitively impaired (<i>n</i> = 115), and cognitively preserved (<i>n</i> = 147) MS patients using receiver operating characteristic analy  ...[more]

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