Ontology highlight
ABSTRACT:
SUBMITTER: Sun H
PROVIDER: S-EPMC6754367 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Sun Hequan H Rowan Beth A BA Flood Pádraic J PJ Brandt Ronny R Fuss Janina J Hancock Angela M AM Michelmore Richard W RW Huettel Bruno B Schneeberger Korbinian K
Nature communications 20190920 1
Meiotic crossovers (COs) ensure proper chromosome segregation and redistribute the genetic variation that is transmitted to the next generation. Large populations and the demand for genome-wide, fine-scale resolution challenge existing methods for CO identification. Taking advantage of linked-read sequencing, we develop a highly efficient method for genome-wide identification of COs at kilobase resolution in pooled recombinants. We first test this method using a pool of Arabidopsis F<sub>2</sub> ...[more]