Ontology highlight
ABSTRACT:
SUBMITTER: Pan Y
PROVIDER: S-EPMC6754518 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Pan Yuchen Y Jiang Zeping Z Sun Dingya D Li Zhenghao Z Pu Yingyan Y Wang Dan D Huang Aijun A He Cheng C Cao Li L
Neuroscience bulletin 20190426 5
The correct differentiation of oligodendrocyte precursor cells (OPCs) is essential for the myelination and remyelination processes in the central nervous system. Determining the regulatory mechanism is fundamental to the treatment of demyelinating diseases. By analyzing the RNA sequencing data of different neural cells, we found that cyclin-dependent kinase 18 (CDK18) is exclusively expressed in oligodendrocytes. In vivo studies showed that the expression level of CDK18 gradually increased along ...[more]