Ontology highlight
ABSTRACT:
SUBMITTER: Duan J
PROVIDER: S-EPMC6756899 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Duan Jiahao J Chen Zijun Z Wu Yeshun Y Zhu Bin B Yang Ling L Yang Chun C
Aging 20190909 17
The prevalence rates of heart failure (HF) are greater than 10% in individuals aged >75 years, indicating an intrinsic link between aging and HF. It has been recognized that mitochondrial dysfunction contributes to the pathology of HF. Mitokines are a type of cytokines, peptides, or signaling pathways produced or activated by the nucleus or the mitochondria through cell non-autonomous responses during cellular stress. In addition to promoting the communication between the mitochondria and the nu ...[more]