Ontology highlight
ABSTRACT:
SUBMITTER: Torocsik B
PROVIDER: S-EPMC6757672 | biostudies-literature | 2002 Oct
REPOSITORIES: biostudies-literature
Töröcsik Béata B Angelastro James M JM Greene Lloyd A LA
The Journal of neuroscience : the official journal of the Society for Neuroscience 20021001 20
We used serial analysis of gene expression to identify new NGF-responsive immediate early genes (IEGs) with potential roles in neuronal differentiation. Among those identified was MafK, a small Maf family basic region and leucine zipper transcriptional repressor and coactivator expressed in immature neurons. NGF treatment elevates the levels of both MafK transcripts and protein. In contrast, there is no effect on expression of the closely related MafG. Unlike many other NGF-responsive IEGs, MafK ...[more]