Ontology highlight
ABSTRACT:
SUBMITTER: Debiais-Thibaud M
PROVIDER: S-EPMC6759074 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Debiais-Thibaud Mélanie M Simion Paul P Ventéo Stéphanie S Muñoz David D Marcellini Sylvain S Mazan Sylvie S Haitina Tatjana T
Molecular biology and evolution 20191001 10
In order to characterize the molecular bases of mineralizing cell evolution, we targeted type X collagen, a nonfibrillar network forming collagen encoded by the Col10a1 gene. It is involved in the process of endochondral ossification in ray-finned fishes and tetrapods (Osteichthyes), but until now unknown in cartilaginous fishes (Chondrichthyes). We show that holocephalans and elasmobranchs have respectively five and six tandemly duplicated Col10a1 gene copies that display conserved genomic synt ...[more]