Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC6759300 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Zhang Youyi Y Ran Zihan Z Tian Miaomiao M Zhou Yang Y Yang Jingcheng J Yin Juan J Lu Daru D Li Rui R Zhong Jiang J
Infection and immunity 20190919 10
As important players in the host defense system, commensal microbes and the microbiota influence multiple aspects of host physiology. <i>Bordetella pertussis</i> infection is highly contagious among humans. However, the roles of the microbiota in <i>B. pertussis</i> pathogenesis are poorly understood. Here, we show that antibiotic-mediated depletion of the microbiota results in increased susceptibility to <i>B. pertussis</i> infection during the early stage. The increased susceptibility was asso ...[more]