Ontology highlight
ABSTRACT:
SUBMITTER: Handa K
PROVIDER: S-EPMC6760231 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Handa Kazuaki K Kiyohara Shuichi S Yamakawa Tomoyuki T Ishikawa Koji K Hosonuma Masahiro M Sakai Nobuhiro N Karakawa Akiko A Chatani Masahiro M Tsuji Mayumi M Inagaki Katsunori K Kiuchi Yuji Y Takami Masamichi M Negishi-Koga Takako T
Scientific reports 20190924 1
Accumulating evidence have shown the association of Parkinson's disease (PD) with osteoporosis. Bone loss in PD patients, considered to be multifactorial and a result of motor disfunction, is a hallmark symptom that causes immobility and decreased muscle strength, as well as malnutrition and medication. However, no known experimental evidence has been presented showing deleterious effects of anti-PD drugs on bone or involvement of dopaminergic degeneration in bone metabolism. Here, we show that ...[more]