Ontology highlight
ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC6761006 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Chen Yabing Y Zhao Xinyang X Wu Hui H
Arteriosclerosis, thrombosis, and vascular biology 20190829 10
Mammalian cells metabolize glucose primarily for energy production, biomass synthesis, and posttranslational glycosylation; and maintaining glucose metabolic homeostasis is essential for normal physiology of cells. Impaired glucose homeostasis leads to hyperglycemia, a hallmark of diabetes mellitus. Chronically increased glucose in diabetes mellitus promotes pathological changes accompanied by impaired cellular function and tissue damage, which facilitates the development of cardiovascular compl ...[more]