Ontology highlight
ABSTRACT:
SUBMITTER: Schneidewind J
PROVIDER: S-EPMC6761149 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Schneidewind Judith J Krause Frank F Bocola Marco M Stadler Andreas Maximilian AM Davari Mehdi D MD Schwaneberg Ulrich U Jaeger Karl-Erich KE Krauss Ulrich U
Communications biology 20190925
Photosynthetic organisms employ two different enzymes for the reduction of the C17 = C18 double bond of protochlorophyllide (Pchlide), yielding the chlorophyll precursor chlorophyllide. First, a nitrogenase-like, light-independent (dark-operative) Pchlide oxidoreductase and secondly, a light-dependent Pchlide oxidoreductase (LPOR). For the latter enzyme, despite decades of research, no structural information is available. Here, we use protein structure modelling, molecular dynamics (MD) simulati ...[more]